Fisetin powder extract from smoke tree, cGMP ISO Factory Supply

High Quality Smoke Tree Extract Fisetin Powder

Smoke tree extract powder Fisetin manufacturer KINTAI - A leader herbal extract supplier in China and certified ISO GMP HACCP qualifications.

KINTAI factory provides high-quality Fisetin powder with best purity test by HPLC.

Our factory have bulk 50%, 98% Fisetin powder in stock for fast delivery, and welcome any spec customization.

We also provide OEM service like private labels, packages. Welcome contact us for further cooperation!

What is Fisetin?

Fisetin is a natural flavonoid compound from the Smoke Tree(Cotinus/Coggygria plant). We also can find Fisetin in vegetables and fruits, such as strawberries, apples, onions, and cucumbers.

It has a wide range of pharmacological activities, such as anti-inflammatory, antioxidant, anti-cancer, anti-thrombosis, neuroprotection, memory improvement, treatment of diabetic kidney damage, etc.

In recent years, studies have found that fisetin has anti-tumor effects. It can inhibit tumor cell proliferation and induce tumor cell apoptosis, which makes it popular in the pharmaceutical intermediates market.

Property of Fisetin

Product name: Fisetin powder

Extract Source: Smoke Tree/Cotinus/Coggygria plant

CAS No: 528-48-3

Chemical formula: C15H10O6

Molecular weight: 286.236

Color: Yellow powder

Solubility: Soluble in ethanol, acetone and acetic acid. Almost insoluble in water, ether.

Storage: Store Fisetin powder in a dry, cool place, avoid the light.

Specification of Fisetin powder

Product Name	Source	CAS No
Fisetin powder	Smoke Tree/Cotinus/Coggygria	528-48-3
Analysis Items	Specification	Test method
Assay of Fisetin	98%	HPLC
Physical and chemical properties
Appearance	Yellow powder	Visual
Odour	Unique	Organoleptic
Particle Size	≥99% Through 80 mesh	Ch.P.C.Rule47
Ash	≤5.0%	Ch.P.C.Rule2302
Loss on drying	≤5.0%	Ch.P.C.Rule52
Heavy Metals of Fisetin	≤10.0ppm	Atomic Absorption
Cadmium(Cd)	≤1.0ppm	Atomic Absorption
Mercury(Hg)	≤0.1ppm	Atomic Absorption
Arsenic(As)	≤1.0ppm	Atomic Absorption
Lead(Pb)	≤2.0ppm	Atomic Absorption
Residual Solvents
– Ethanol	≤1000 PPM	Gas Chromatography
Microbiological Quality (Total viable aerobic count) of Fisetin powder
Total Plate Count,cfu/g	≤1000 CFU/g	Ch.P.C.Rule80
Mold and yeast Count,cfu/g	≤ 100 CFU/g	Ch.P.C.Rule80
E. coli	Negative	Ch.P.C.Rule80
Salmonella	Negative	Ch.P.C.Rule80
Staphylococcus aureus	Negative	Ch.P.C.Rule80
*Storage Condition: Store in tightly closed plastic bag and keep in a cool dry place. Keep always from strong direct light.
*KINTAI Promise All Products: Non-Irradiated / Non-ETO/ Treat by Heat Only / Non-GMO

Function and Application

Smoke tree extract Fisetin powder is a natural product that has various pharmacological effects such as anti-inflammatory, anti-cancer and cardiovascular effects.

Fisetin powder from our factory is mainly used as a medical raw material in the field of disease treatment, or add to healthcare supplements by its anti-oxidation and neuroprotective function.

Main Function of Fisetin powder

1. Anti-oxidation

Fisetin is a natural antioxidant that cleans free radicals in the body, therefore reducing oxidative stress.

Oxidative stress is an important reason for the occurrence and development of many diseases, such as cardiovascular disease, diabetes, cancer, etc.

Studies have found that fisetin can reduce peroxidized lipid levels in blood and increase the activity of antioxidant enzymes, such as superoxide dismutase (SOD), glutathione peroxidase (GPx), etc. In addition, fisetin powder can inhibit the oxidation of low-density lipoprotein (LDL), thus reducing the risk of atherosclerosis.

2. Anti-inflammatory

Fisetin has good anti-inflammatory effects and can inhibit inflammatory reactions and the release of inflammatory mediators.

Fisetin powder can inhibit the production of inflammatory cytokines, such as interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), etc. In addition, fisetin can also inhibit the activation of nuclear transcription factor-κB (NF-κB), thereby reducing the inflammatory response.

3. Anti-cancer

Natural smoke tree extract fisetin has an inhibitory effect on a variety of tumor cells. It can inhibit the growth and spread of tumor cells, prevent the proliferation of breast cancer, cervical cancer, blood cancer, and other cancer cells, finally promote apoptosis.

In addition, fisetin can also enhance the efficacy of radiotherapy and chemotherapy, so it is an anti-cancer agent with development potential.

Fisetin has the characteristics of wide distribution of extraction sources, low toxicity, low side effects, and multiple active pathways. It is believed that with continuous research, it can be more effectively used in clinical applications and serve human health better.

4. Cardiovascular protection

Cardiovascular disease is one of the leading reasons of death worldwide. Fisetin has cardiovascular protective effects and can reduce the risk of occurrence and development of cardiovascular diseases. Studies have found that fisetin can reduce plasma cholesterol and triglyceride levels and improve dyslipidemia. In addition, fisetin can inhibit platelet aggregation and reduce the risk of thrombosis. At the same time, fisetin can also dilate coronary arteries and increase myocardial blood flow, thereby improving myocardial ischemia.

5. Neuroprotective

Firstly, fisetin has neuroprotective effects by inhibiting oxidative stress, inflammatory response, mitochondrial dysfunction and other pathways. In addition, fisetin powder can also promote the regeneration and repair of nerve cells and improve nerve function.

Secondly, natural fisetin extract powder from our factory can improve brain health, cognition, and memory function. Fisetin stimulates and helps brain circuits and brain signaling pathways related to memory function. It also helps brain cell growth and protects brain cells from oxidative damage.