Macleaya Cordata extract Sanguinarine, Chelerythrine cGMP

KINTAI's High Quality Macleaya Cordata Extract

Macleaya Cordata extract (MCE) manufacturer KINTAI is a leader herbal extract company in China and certified ISO GMP HACCP qualifications.

We have the pure macleaya cordata extract contain total alkali 60%: Sanguinarine 40%, Chelerythrine 20%.

We also provide customization service, welcome contact us for further information!

What is Macleaya Cordata?

English Name: Macleaya cordata, Pink Plumepoppy, Plume-poppy

Scientific Name: Macleaya cordata (Willd.) R. Brown、Bocconia cordata Willd.

Origin:

Macleaya cordata plant is native to China and is mainly distributed in the Yangtze River Basin of China, extending to Guangdong in the south, Guizhou in the west, and southern Gansu in the northwest. It is also distributed in Japan and India. Born in hills, forests, jungles and shrubs at an altitude of 150 to 830 meters.

Feature:

The stems of macleaya cordata plant can be as high as 2 meters. The stems are hollow, the surface is smooth and mostly covered with white powder. The green leaves are usually wide oval or nearly round, with wavy, notched or coarse teeth on the edges, and the back side is usually gray and white. Covered with fine hairs that fall off easily.

Growing environment:

The macleaya cordata plant likes a warm and humid environment, prefers sunny places, likes fertilizer, is afraid of waterlogging, has strong drought tolerance and cold resistance, and is not strict with soil, but needs fertile, loose, and well-drained soil. Growing vigorously. The suitable growth temperature is 22-28℃.

Chemical components:

The main chemical components of macleaya cordata plant: alkaloids, including Sanguinarine, chelerythrine, protopine, α-Allocryptopine and β -Allocrytopine (β-Allocrytopine).

Functions:

Macleaya cordata has the functions of anti-inflammatory, detoxification, reduce swelling and insecticide. Modern pharmacological research shows that as the main active ingredient of Macleaya cordata extract, sanguinarine plays an important role in the treating various inflammations.

External use to treat boils, abscesses, hemorrhoids, and eczema. It can also treat snake bites, bruises, rheumatic joint pain, toothache, otitis media, burns, scalds, ringworm, acute tonsillitis, and lower limb ulcers.

Macleaya Cordata Extract

Active Ingredients: Sanguinarine, Chelerythrine

The main bioactive substances in macleaya cordata plant are alkaloids, mainly are both sanguinarine and chelerythrine, with the highest content.

Function:

Antibacterial, insecticidal, maggoticidal, antiviral, anti-inflammatory, anti-tumor, improved liver function, and enhanced immunity effects.

Application:

Macleaya Cordata extract is widely used in medicine, chemical product raw materials, biopesticides, veterinary drugs, and animal breeding.

In 2004, products with sanguinarine and chelerythrine extracted from the macleaya cordata plant as the main ingredients were registered in the EU as feed additive Sangrovit, and are widely used in 74 countries and regions around the world to promote animal growth and improve animal health, antibiotic alternative.

In China, products with sanguinarine and chelerythrine as main ingredients have been developed into national Class II new Chinese veterinary drugs. Due to it has significant effects in replacing growth-promoting antibiotics in feeding, improving animal growth performance, and improving animal health.

Specification

Product Name	Source	Active Ingredient
Macleaya Cordata Extract	Macleaya Cordata plant	Alkaloids,Sanguinarine,Chelerythrine
Analysis Items	Specification	Test method
Assay of Alkaloids	Total Alkali Min.60%. Sanguinarine Min.40%. Chelerythrine Min.20%.	HPLC
Physical and chemical properties
Appearance	Orange red powder	Visual
Odour	Unique	Organoleptic
Particle Size	≥99% Through 80 mesh	Ch.P.C.Rule47
Ash	≤5.0%	Ch.P.C.Rule2302
Loss on drying	≤5.0%	Ch.P.C.Rule52
Heavy Metals of Macleaya Cordata Extract	≤10.0ppm	Atomic Absorption
Cadmium(Cd)	≤1.0ppm	Atomic Absorption
Mercury(Hg)	≤0.1ppm	Atomic Absorption
Arsenic(As)	≤1.0ppm	Atomic Absorption
Lead(Pb)	≤2.0ppm	Atomic Absorption
Residual Solvents
– Ethanol	≤1000 PPM	Gas Chromatography
Microbiological Quality (Total viable aerobic count) of Macleaya Cordata Extract
Total Plate Count,cfu/g	≤1000 CFU/g	Ch.P.C.Rule80
Mold and yeast Count,cfu/g	≤ 100 CFU/g	Ch.P.C.Rule80
E. coli	Negative	Ch.P.C.Rule80
Salmonella	Negative	Ch.P.C.Rule80
Staphylococcus aureus	Negative	Ch.P.C.Rule80
*Storage Condition: Store in tightly closed plastic bag and keep in a cool dry place. Do not freeze. Keep always from strong direct light.
*KINTAI Promise All Products: Non-Irradiated / Non-ETO/ Treat by Heat Only / Non-GMO

Applications In Animals Feeding

Poultry

The active ingredients of macleaya cordata extract can increase the feed intake and weight gain of poultry, also improve intestinal health, and increase grain digestibility; Meanwhile enhance the body's resistance and prevent disease infections; increase the egg production rate of laying poultry, and reduce Mortality and other effects.

Pig

The macleaya cordata extract application in pig breeding is mainly in the stages of weaning piglets, growing pigs, late pregnancy and lactation sows. It has the effects of promoting growth, resisting stress and improving intestinal health.

Aquatic animal

The functional ingredients of macleaya cordata extract can kill various parasites that threaten the survival of aquatic animals such as schistosomiasis, ringworm, and melonworm, and have growth-promoting and Improve immunity, improve health and other effects.

Ruminants

Udder inflammation not only causes a decrease in milk production of dairy cows, but also reduces the quality of dairy products. The functional ingredients of macleaya cordata extract have good anti-inflammatory activity, which can improve mastitis in dairy cows and improve the quality of milk production.